Validation of MRC Centre MRI calf muscle fat fraction protocol as an outcome measure in CMT1A
نویسندگان
چکیده
منابع مشابه
Functional Muscle MRI in Human Calf Muscle using IVIM
Introduction Diffusion Weighted Imaging (DWI) is increasingly gaining importance for a variety of clinical applications, and derived apparent diffusion coefficients (ADC) based on DWI data have been reported in a multitude of studies [1]. In biologic tissues, ADC is determined by the microscopic motion of water, including not only translational and rotational molecular diffusion but also microc...
متن کاملCognition as an outcome measure in schizophrenia.
BACKGROUND Cognitive deficits are a core feature of schizophrenia. These deficits are not caused by medication or symptoms, and have a dramatic negative effect on real-world functioning. AIMS To critically examine a selection of the most common batteries used to assess cognition in schizophrenia. METHOD Literature review of cognitive assessment batteries for use in schizophrenia. RESULTS ...
متن کاملQuality of life as an outcome measure.
It is important to identify unknown and unquantified benefits and risks of therapeutic intervention that are reflected in the quality of life. This is especially important when the benefit : risk analysis is not clearly in favour of treatment. Quality of life is defined and target areas identified. The steps in the measurements of quality of life are discussed, including the validity, repeatabi...
متن کاملMRI biomarker assessment of neuromuscular disease progression: a prospective observational cohort study
BACKGROUND A substantial impediment to progress in trials of new therapies in neuromuscular disorders is the absence of responsive outcome measures that correlate with patient functional deficits and are sensitive to early disease processes. Irrespective of the primary molecular defect, neuromuscular disorder pathological processes include disturbance of intramuscular water distribution followe...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neurology
سال: 2018
ISSN: 0028-3878,1526-632X
DOI: 10.1212/wnl.0000000000006214